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Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts

23 Feb 2018

Abstract excerpt

Osteoporosis is a complex disease with a strong genetic component. Genomewide association studies (GWAS) have been very successful at identifying common genetic variants associated with bone parameters. A recently published study documented the results of the largest GWAS for bone mineral density (BMD) performed to date (n = 142,487), identifying 307 conditionally independent single-nucleotide polymorphisms...

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PMID: 29473973
DOI: 10.1002/jbmr.3412

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