Article

Integrating genome-wide association and transcriptome predicted model identify novel target genes with osteoporosis

2019-09-16

Abstract excerpt

Osteoporosis (OP) is a highly polygenetic disease which is usually characterized by low bone mineral density. Genome-wide association studies (GWAS) have identified hundreds of genetic loci associated with bone mineral density. However, the biological mechanisms of these loci remain elusive. To identify potential causal genes of the associated loci, we detected trait-gene expression associations by transcriptome-w...

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Literature Corpus work: a20db67b-724c-5c97-98cb-3cae2fbd4219
DOI: 10.1101/771543

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