Article

High-resolution genome-wide functional dissection of transcriptional regulatory regions in human

2017-09-27

Abstract excerpt

Genome-wide epigenomic maps revealed millions of regions showing signatures of enhancers, promoters, and other gene-regulatory elements 1 . However, high-throughput experimental validation of their function and high-resolution dissection of their driver nucleotides remain limited in their scale and length of regions tested. Here, we present a new method, HiDRA (High-Definition Reporter Assay), that overcomes thes...

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Literature Corpus work: 338ab750-12ae-5d25-9270-0e7597a57697
DOI: 10.1101/193136

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