Article

Prioritization of osteoporosis-associated GWAS SNPs using epigenomics and transcriptomics

2020-06-18

Abstract excerpt

Genetic risk factors for osteoporosis, a prevalent disease associated with aging, have been examined in many genome-wide association studies (GWAS). A major challenge is to prioritize transcription-regulatory GWAS-derived variants that are likely to be functional. Given the critical role of epigenetics in gene regulation, we have used an unusual epigenetics- and transcription-based approach to identify credible re...

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Literature Corpus work: 4b9fee14-c4eb-5c34-9dec-11a80e2cd0fd
DOI: 10.1101/2020.06.18.160309

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