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Inhibitory Circuit Compensations in Female and Male Mice: Increased Synaptic Output Offsets Reduced Parvalbumin Interneuron Density

2025-05-21

Abstract excerpt

<h4>Summary</h4> Parvalbumin inhibitory interneurons (PV-INs) are critical regulators of excitatory/inhibitory balance in the cortex, and their dysfunction has been observed in various neurological disorders. Despite increasing recognition of sex differences in brain function, little is known about how PV-INs differ between males and females under healthy conditions. Previous work has pointed to sex differences i...

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Literature Corpus work
156031b9-9f20-5bf8-910f-92456a649460
DOI
10.1101/2025.05.20.655207
Open publication

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Inhibitory Circuit Compensations in Female and Male Mice: Increased Synaptic Output Offsets Reduced Parvalbumin Interneuron DensityDOI 10.1101/2025.05.20.655207
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