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Transcriptomic analysis reveals sex-specific patterns in the hippocampus in Alzheimer’s disease

16 Apr 2024

Abstract excerpt

Background The hippocampus, vital for memory and learning, is among the first brain regions affected in Alzheimer’s Disease (AD) and exhibits adult neurogenesis. Women face twice the risk of developing AD compare to men, making it crucial to understand sex differences in hippocampal function for comprehending AD susceptibility. Methods We conducted a comprehensive analysis of bulk mRNA postmortem samples from the...

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PMID: 38689734
DOI: 10.3389/fendo.2024.1345498

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