Article

A roadmap to human hippocampal neurogenesis in adulthood, aging and AD.

2024-05-30

Abstract excerpt

<title>Abstract</title> <p> In the rodent, hippocampal neurogenesis plays critical roles in learning and memory <sup>1,2</sup> , is tightly regulated by inhibitory neurons <sup>3-7</sup> and contributes to memory dysfunction in Alzheimer’s disease (AD) mouse models <sup>8-10</sup> . In contrast, the mechanisms regulating neurogenesis in the adult human hippocampus, the dynamic shifts in the transcriptomic...

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Literature Corpus work: 2f6dc024-4307-50a6-b363-d88df6c17693
DOI: 10.21203/rs.3.rs-4469965/v1

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