Article

Ancestrally diverse genome-wide association analysis highlights ancestry-specific differences in genetic regulation of plasma protein levels

2024-09-28

Abstract excerpt

Fully characterizing the genetic architecture of circulating proteins in multi-ancestry populations provides an unprecedented opportunity to gain insights into the etiology of complex diseases. We characterized and contrasted the genetic associations of plasma proteomes in 9,455 participants of European and African (19.8%) ancestry from the Atherosclerosis Risk in Communities Study. Of 4,651 proteins, 1,408 and 2,...

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Literature Corpus work: 47aeeb78-a71d-53cc-8a4e-c2d01eddd2cd
DOI: 10.1101/2024.09.27.24314500

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