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Article

Whole genome sequencing analysis of the cardiometabolic proteome

2019-11-27

Abstract excerpt

The human proteome is a crucial intermediate between complex diseases and their genetic and environmental components, and an important source of drug development targets and biomarkers. Here, we comprehensively assess the genetic architecture of 257 circulating protein biomarkers of cardiometabolic relevance through high-depth (22.5x) whole-genome sequencing (WGS) in 1,328 individuals. We discover 131 independent...

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Literature Corpus work
b8cc3aa5-69f7-51d4-b149-73722c322412
DOI
10.1101/854752
Open publication

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Whole genome sequencing analysis of the cardiometabolic proteomeDOI 10.1101/854752
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