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Translocation-driven chr19-der(14) interaction is associated with disease-specific transcriptional programs in mantle cell lymphoma

2026-06-09

Abstract excerpt

<h4>ABSTRACT</h4> Mantle cell lymphoma (MCL) is defined by the t(11;14)(q13;q32) translocation, which drives constitutive CCND1 expression, yet the broader regulatory consequences of this rearrangement remain incompletely understood. Here, we combined transcriptomic, epigenomic, Hi-C, and 3D-FISH analyses in primary MCL samples and cell lines to investigate the genome-wide impact of t(11;14) on chromatin organiz...

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Literature Corpus work
44e575c4-565f-5407-ac43-cd7818ed4ac0
DOI
10.64898/2026.06.05.730311
Open publication

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Translocation-driven chr19-der(14) interaction is associated with disease-specific transcriptional programs in mantle cell lymphomaDOI 10.64898/2026.06.05.730311
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