Article

Systematic analysis of the molecular and biophysical properties of key DNA damage response factors

2022-06-09

Abstract excerpt

<h4>ABSTRACT</h4> Repair of DNA double strand breaks (DSBs) is integral to preserving genomic integrity. Therefore, defining the mechanisms underlying DSB repair will enhance our understanding of how defects in these pathways contribute to human disease and could lead to the discovery of new approaches for therapeutic intervention. Here, we established a panel of HaloTagged DNA damage response factors in U2OS cel...

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Literature Corpus work: 4358d6d1-766a-58ea-9bb8-68107ed348f1
DOI: 10.1101/2022.06.09.495359

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