Article

Genome-wide mapping of native co-localized G4s and R-loops in living cells

2024-06-04

Abstract excerpt

The non-B DNA structures can act as dynamic functional genomic elements regulating gene expression. Among them, G4s and R-loops are two of the best studied. The interplay between R-loops and G4s are emerging in regulating DNA repair, replication and transcription. A comprehensive picture of native co-localized G4s and R-loops in living cells is currently lacking. Here, we describe the development of HepG4-seq and...

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Literature Corpus work: 481d1d0c-4fe9-59b7-ba28-77eaf404fe3f
DOI: 10.1101/2024.06.03.597194

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