Article

The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination within heterochromatin

2018-12-21

Abstract excerpt

<h4>ABSTRACT</h4> Efficient double-strand break repair in eukaryotes requires manipulation of chromatin structure. ATP-dependent chromatin remodelling enzymes can facilitate different DNA repair pathways, during different stages of the cell cycle and in a range of chromatin environments. The contribution of remodelling factors to break repair within heterochromatin during G2 is unclear. The human HELLS protein is...

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Literature Corpus work: 1d67bb37-1468-5f92-b7a1-8853ef0e8c8e
DOI: 10.1101/504043

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