Article

The effect of genetically proxied IL-6 signalling on severe malaria: A Mendelian randomisation analysis

2022-11-10

Abstract excerpt

<h4>Introduction</h4> Severe malaria remains a deadly disease for many young children in low- and middle-income countries. Levels of Interleukin-6 (IL-6) have been shown to identify cases of severe malaria and associate with severity, but it is unknown if this association is causal, or whether manipulation of IL-6 might alter outcomes in severe malaria. <h4>Methods</h4> A single nucleotide polymorphism (SNP, rs222...

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Literature Corpus work: 40e19f68-5769-5f67-bb3c-a8fe2580d8f1
DOI: 10.1101/2022.11.04.22281934

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