Article
How malaria has affected the human genome and what human genetics can teach us about malaria.
American journal of human genetics - 1 Aug 2005
Kwiatkowski Dominic P
Abstract excerpt
Malaria is a major killer of children worldwide and the strongest known force for evolutionary selection in the recent history of the human genome. The past decade has seen growing evidence of ethnic differences in susceptibility to malaria and of the diverse genetic adaptations to malaria that have arisen in different populations: epidemiological confirmation of the hypotheses that G6PD deficiency, alpha+...
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