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Article

Candidate human genetic polymorphisms and severe malaria in a Tanzanian population.

PloS one - 1 Jan 2012

Manjurano Alphaxard, Clark Taane G, Nadjm Behzad, Mtove George, Wangai Hannah, Sepulveda Nuno, Campino Susana G, Maxwell Caroline, Olomi Raimos, Rockett Kirk R, Jeffreys Anna, Riley Eleanor M, Reyburn Hugh, Drakeley Christopher

Abstract excerpt

Human genetic background strongly influences susceptibility to malaria infection and progression to severe disease and death. Classical genetic studies identified haemoglobinopathies and erythrocyte-associated polymorphisms, as protective against severe disease. High throughput genotyping by mass spectrometry allows multiple single nucleotide polymorphisms (SNPs) to be examined simultaneously. We compared the...

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PMID: 23144702
DOI: 10.1371/journal.pone.0047463
PMCID: PMC3483265

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ADCY9
RTN3
TRIM5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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