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Article

Genome-wide heritability analysis of severe malaria resistance reveals evidence of polygenic inheritance.

Human molecular genetics - 1 Jan 2020

Damena Delesa, Chimusa Emile R

Abstract excerpt

BACKGROUND: Estimating single nucleotide polymorphism (SNP)-heritability (h2g) of severe malaria resistance and its distribution across the genome might shed new light in to the underlying biology. METHOD: We investigated h2g of severe malaria resistance from a genome-wide association study (GWAS) dataset (sample size = 11 657). We estimated the h2g and partitioned in to chromosomes, allele frequencies and...

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Identifiers

PMID: 31691794
DOI: 10.1093/hmg/ddz258
PMCID: PMC7416678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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