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Functional analysis of genome-wide dataset from 17000 individuals identifies multiple candidate malaria resistance genes enriched in malaria pathogenic pathways

2020-08-17

Abstract excerpt

Recent genome-wide association studies (GWASs) of severe malaria have identified several association variants. However, much about the underlying biological functions are yet to be discovered. Here, we systematically predicted plausible candidate genes and pathways from functional analysis of severe malaria resistance GWAS summary statistics (N = 17,000) metaanalyzed across eleven populations in malaria endemic re...

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Literature Corpus work
dffc12fa-59a9-517a-a352-db0598736aa0
DOI
10.1101/2020.08.15.20175471
Open publication

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Functional analysis of genome-wide dataset from 17000 individuals identifies multiple candidate malaria resistance genes enriched in malaria pathogenic pathwaysDOI 10.1101/2020.08.15.20175471
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