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Genetics of Malaria Inflammatory Responses: A Pathogenesis Perspective

30 Jul 2019

Abstract excerpt

infections remains a global public health concern. Only a fraction of infected people develops severe clinical syndromes motivating a longstanding search for genetic determinants of malaria severity. Strong genetic effects have been repeatedly ascribed to mutations and allelic variants of proteins expressed in red blood cells but the role of inflammatory response genes in disease pathogenesis has been difficult...

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PMID: 31417551
DOI: 10.3389/fimmu.2019.01771

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