Article

De novo identification of CD4+ T cell epitopes

2022-11-21

Abstract excerpt

<h4>ABSTRACT</h4> CD4+ T cells recognize peptide antigens presented on class II Major Histocompatibility Complex (MHC-II) molecules to carry out their function. The remarkable diversity of T cell receptor (TCR) sequences and lack of antigen discovery approaches for MHC-II make profiling the specificities of CD4+ T cells challenging. We have expanded our platform of Signaling and Antigen-presenting Bifunctional Re...

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Literature Corpus work: 40da8b6d-180b-5516-abaa-c4f97fa1d9c9
DOI: 10.1101/2022.11.21.517373

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