Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Using the T Cell Receptor as a Biomarker in Type 1 Diabetes.

Frontiers in immunology - 1 Jan 2021

Nakayama Maki, Michels Aaron W

Abstract excerpt

T cell receptors (TCRs) are unique markers that define antigen specificity for a given T cell. With the evolution of sequencing and computational analysis technologies, TCRs are now prime candidates for the development of next-generation non-cell based T cell biomarkers, which provide a surrogate measure to assess the presence of antigen-specific T cells. Type 1 diabetes (T1D), the immune-mediated form of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to Disease Susceptibility
Share to Epitopes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens

Share to Islets of Langerhans

Share to Peptides

Share to Receptors, Antigen, T-Cell

Share to T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 34868047
DOI: 10.3389/fimmu.2021.777788
PMCID: PMC8635517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Using the T Cell Receptor as a Biomarker in Type 1 Diabetes.PMID 34868047Read ↗

Unbiased discovery of autoreactive type 1 diabetes T-cell receptors that bind specific hybrid insulin peptidesSemantic proximity Read ↗

Tracking DNA-based antigen-specific T cell receptors during progression to type 1 diabetesSemantic proximity Read ↗

Identification of a type 1 diabetes-associated T cell receptor repertoire signature from the human peripheral blood.Semantic proximity Read ↗

Identification of a type 1 diabetes-associated T cell receptor repertoire signature from the human peripheral bloodSemantic proximity Read ↗

Insights From Single Cell RNA Sequencing Into the Immunology of Type 1 Diabetes- Cell Phenotypes and Antigen Specificity.Semantic proximity Read ↗

The Type 1 Diabetes T Cell Receptor and B Cell Receptor Repository in the AIRR Data Commons: a practical guide for access, use and contributions through the Type 1 Diabetes AIRR ConsortiumSemantic proximity Read ↗

Self-reactive germline-like TCR alpha chains shared between blood and pancreasSemantic proximity Read ↗

Autoimmune CD8+ T cells in type 1 diabetes: from single-cell RNA sequencing to T-cell receptor redirectionSemantic proximity Read ↗

The Role of T Cell Receptor Signaling in the Development of Type 1 DiabetesSemantic proximity Read ↗

Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ DonorsSemantic proximity Read ↗

Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians.Semantic proximity Read ↗

Temporal development of T cell receptor repertoires during childhood in health and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.