Article

TCRMatch: Predicting T-cell receptor specificity based on sequence similarity to previously characterized receptors

2020-12-11

Abstract excerpt

<h4>ABSTRACT</h4> The adaptive immune system in vertebrates has evolved to recognize non-self-antigens, such as proteins expressed by infectious agents and mutated cancer cells. T cells play an important role in antigen recognition by expressing a diverse repertoire of antigen-specific receptors, which bind epitopes to mount targeted immune responses. Recent advances in high-throughput sequencing have enabled the...

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Literature Corpus work: 407dc9b3-6a68-5e89-b626-18986b3eae40
DOI: 10.1101/2020.12.11.418426

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