Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insights From Single Cell RNA Sequencing Into the Immunology of Type 1 Diabetes- Cell Phenotypes and Antigen Specificity.

Frontiers in immunology - 1 Jan 2021

Hanna Stephanie J, Tatovic Danijela, Thayer Terri C, Dayan Colin M

Abstract excerpt

In the past few years, huge advances have been made in techniques to analyse cells at an individual level using RNA sequencing, and many of these have precipitated exciting discoveries in the immunology of type 1 diabetes (T1D). This review will cover the first papers to use scRNAseq to characterise human lymphocyte phenotypes in T1D in the peripheral blood, pancreatic lymph nodes and islets. These have revealed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens
Share to Biomarkers
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Receptors, Antigen, B-Cell

Share to Receptors, Antigen, T-Cell

Share to Sequence Analysis, RNA

Share to Single-Cell Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 34659258
DOI: 10.3389/fimmu.2021.751701
PMCID: PMC8519581

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insights From Single Cell RNA Sequencing Into the Immunology of Type 1 Diabetes- Cell Phenotypes and Antigen Specificity.PMID 34659258Read ↗

Lessons from single-cell RNA sequencing of human isletsSemantic proximity Read ↗

PanKbase Integrated Single-Cell Map: A Comprehensive Atlas of Human Pancreatic IsletsSemantic proximity Read ↗

Using the T Cell Receptor as a Biomarker in Type 1 Diabetes.Semantic proximity Read ↗

Deciphering the Transcriptomic Landscape of Type 2 Diabetes: Insights from Bulk RNA Sequencing and Single-Cell AnalysisSemantic proximity Read ↗

Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.Semantic proximity Read ↗

Systematic immune cell dysregulation and molecular subtypes revealed by single-cell RNA-seq of subjects with type 1 diabetesSemantic proximity Read ↗

Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onsetSemantic proximity Read ↗

Multiomics single-cell analysis of human pancreatic islets reveals novel cellular states in health and type 1 diabetesSemantic proximity Read ↗

Single-cell RNA sequencing reveals the dysfunctional characteristics of PBMCs in patients with type 2 diabetes mellitusSemantic proximity Read ↗

Identification of a type 1 diabetes-associated T cell receptor repertoire signature from the human peripheral blood.Semantic proximity Read ↗

Tracking DNA-based antigen-specific T cell receptors during progression to type 1 diabetesSemantic proximity Read ↗

Identification of a type 1 diabetes-associated T cell receptor repertoire signature from the human peripheral bloodSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.