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Identification of a Lipid Oxygen Radical Defense pathway and its epigenetic control

2025-02-27

Abstract excerpt

<h4>ABSTRACT</h4> Membrane phospholipids are vulnerable to oxidative radicals, and uncontrolled lipid peroxidation affects cell viability. Cells have evolved quality control and defense mechanisms, of which the genetic regulation is not fully understood. Here, we identify what we have coined the Lipid Oxygen Radical Defense (LORD) pathway. It is epigenetically repressed by a complex comprising the KRAB-zinc finge...

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Identifiers and source

Literature Corpus work
3fd3c830-5840-5b55-9935-cdf7101d1a54
DOI
10.1101/2025.02.25.640160
Open publication

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Identification of a Lipid Oxygen Radical Defense pathway and its epigenetic controlDOI 10.1101/2025.02.25.640160
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