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Article

Epigenetic Regulation of Ferroptosis-Associated Genes and Its Implication in Cancer Therapy

31 Jan 2022

Abstract excerpt

Ferroptosis is an evolutionarily conserved form of regulated cell death triggered by iron-dependent phospholipid peroxidation. Ferroptosis contributes to the maintenance of tissue homeostasis under physiological conditions while its aberration is tightly connected with lots of pathophysiological processes such as acute tissue injury, chronic degenerative disease, and tumorigenesis. Epigenetic regulation controls...

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PMID: 35174081
DOI: 10.3389/fonc.2022.771870

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