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The Intersection of DNA Damage Response and Ferroptosis—A Rationale for Combination Therapeutics

23 Jul 2020

Abstract excerpt

Ferroptosis is a novel form of iron-dependent cell death characterized by lipid peroxidation. While the importance and disease relevance of ferroptosis are gaining recognition, much remains unknown about its interaction with other biological processes and pathways. Recently, several studies have identified intricate and complicated interplay between ferroptosis, ionizing radiation (IR), ATM (ataxia-telangiectasia...

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PMID: 32718025
DOI: 10.3390/biology9080187

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