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Adaptation of the tetracycline-repressible system for modulating the expression of essential genes in <i>Cryptococcus neoformans</i>

2024-11-30

Abstract excerpt

The opportunistic human fungal pathogen Cryptococcus neoformans has an enormous impact on human health as the causative agent of cryptococcal meningitis, an AIDS-defining illness that results in significant human mortality. To combat C. neoformans infections, there is a dire need to expand our current antifungal arsenal. Essential gene products often serve as ideal targets for antimicrobials, and thus identifyin...

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Literature Corpus work
3f5082ec-865f-5467-8088-afa409ac8fc4
DOI
10.1101/2024.11.29.626100
Open publication

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