Article

Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology

2024-10-22

Abstract excerpt

<h4>SUMMARY</h4> Cryptococcus neoformans is the most common cause of fungal meningitis and the top-ranked W.H.O. priority fungal pathogen. Only distantly related to model fungi, C. neoformans is also a powerful experimental system for exploring conserved eukaryotic mechanisms lost from specialist model yeast lineages. To decipher its biology globally, we constructed 4328 gene deletions and measured—with exceptio...

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Literature Corpus work: 412d790f-ce71-53f0-9cec-608b2249ad28
DOI: 10.1101/2024.10.22.619677

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