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Saturation transposon mutagenesis enables genome-wide identification of genes required for growth and fluconazole resistance in the human fungal pathogen <i>Cryptococcus neoformans</i>

2024-07-29

Abstract excerpt

Fungi can cause devastating invasive infections, typically in immunocompromised patients. Treatment is complicated both by the evolutionary similarity between humans and fungi and by the frequent emergence of drug resistance. Studies in fungal pathogens have long been slowed by a lack of high-throughput tools and community resources that are common in model organisms. Here we demonstrate a high-throughput transpos...

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Literature Corpus work
e4579505-6ba3-51a0-b00f-1dc570f06fe8
DOI
10.1101/2024.07.28.605507
Open publication

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Saturation transposon mutagenesis enables genome-wide identification of genes required for growth and fluconazole resistance in the human fungal pathogen <i>Cryptococcus neoformans</i>DOI 10.1101/2024.07.28.605507
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