Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential Gene Discovery in the Basidiomycete Cryptococcus neoformans for Antifungal Drug Target Prioritization

1 Apr 2015

Abstract excerpt

UNLABELLED: Fungal diseases represent a major burden to health care globally. As with other pathogenic microbes, there is a limited number of agents suitable for use in treating fungal diseases, and resistance to these agents can develop rapidly. Cryptococcus neoformans is a basidiomycete fungus that causes cryptococcosis worldwide in both immunocompromised and healthy individuals. As a basidiomycete, it diverged...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fungal and yeast genetics research
Share to Fungal Infections and Studies
Share to Nail Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25827419
DOI: 10.1128/mbio.02334-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential Gene Discovery in the Basidiomycete Cryptococcus neoformans for Antifungal Drug Target PrioritizationPMID 25827419Read ↗

Essential genes encoded by the mating-type locus of the human fungal pathogen Cryptococcus neoformans.Semantic proximity Read ↗

Essential genes encoded by the mating-type locus of the human fungal pathogen <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targetsSemantic proximity Read ↗

Comparative genomics allowed the identification of drug targets against human fungal pathogensSemantic proximity Read ↗

Landscape of essential growth and fluconazole-resistance genes in the human fungal pathogen Cryptococcus neoformansSemantic proximity Read ↗

Saturation transposon mutagenesis enables genome-wide identification of genes required for growth and fluconazole resistance in the human fungal pathogen <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Isolation of conditional mutations in genes essential for viability of Cryptococcus neoformans.Semantic proximity Read ↗

Phenotypic landscape of a fungal meningitis pathogen reveals its unique biologySemantic proximity Read ↗

Phenotypic landscape of an invasive fungal pathogen reveals its unique biology.Semantic proximity Read ↗

Adaptation of the tetracycline-repressible system for modulating the expression of essential genes in <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Monogenetic causes of fungal disease: recent developments.Semantic proximity Read ↗

The enigmatic role of fungal annexins: the case of <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.