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The copper regulon of the human fungal pathogen<i>Cryptococcus neoformans</i>H99

8 Aug 2011

Abstract excerpt

Cryptococcus neoformans is a human fungal pathogen that is the causative agent of cryptococcosis and fatal meningitis in immuno-compromised hosts. Recent studies suggest that copper (Cu) acquisition plays an important role in C. neoformans virulence, as mutants that lack Cuf1, which activates the Ctr4 high affinity Cu importer, are hypo-virulent in mouse models. To understand the constellation of Cu-responsive...

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PMID: 21819456
DOI: 10.1111/j.1365-2958.2011.07794.x

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The copper regulon of the human fungal pathogen<i>Cryptococcus neoformans</i>H99PMID 21819456Read ↗

Genome‐wide analysis of the regulation of Cu metabolism in Cryptococcus neoformansSemantic proximity Read ↗

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