Article

Muscle cofilin alters neuromuscular junction postsynaptic development to strengthen functional neurotransmission

2023-11-22

Abstract excerpt

Cofilin, an actin severing protein, plays critical roles in muscle sarcomere addition and maintenance. Our previous work has shown Drosophila cofilin ( DmCFL ) knockdown causes progressive deterioration of muscle structure and function and produces features seen in nemaline myopathy (NM) caused by cofilin mutations. We hypothesized that disruption of actin cytoskeleton dynamics by DmCFL knockdown would impact o...

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Literature Corpus work: 3a4ceea0-9a81-5ecf-9f1d-8bad0e2ccb83
DOI: 10.1101/2023.11.21.568166

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