Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila twinfilin is required for cell migration and synaptic endocytosis.

Journal of cell science - 1 May 2010

Wang Dan, Zhang Lijun, Zhao Guoli, Wahlström Gudrun, Heino Tapio I, Chen Jiong, Zhang Yong Q

Abstract excerpt

Precise actin regulation is essential for diverse cellular processes such as axonal growth, cell migration and endocytosis. twinfilin (twf) encodes a protein that sequesters actin monomers, but its in vivo functions are unclear. In this study, we characterized twf-null mutants in a metazoan for the first time and found that Drosophila twf negatively regulates F-actin formation in subcellular regions of rapid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exocytosis
Share to Axons
Share to Neurotransmitter Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ovarian Follicle

Share to Profilins

Share to Receptors, Glutamate

Share to Synapses

Share to Synaptic Transmission

Source

Identifiers

PMID: 20410372
DOI: 10.1242/jcs.060251

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila twinfilin is required for cell migration and synaptic endocytosis.PMID 20410372Read ↗

Highwire regulates synaptic growth in Drosophila.Semantic proximity Read ↗

Muscle cofilin alters neuromuscular junction postsynaptic development to strengthen functional neurotransmissionSemantic proximity Read ↗

Knock-out of Tpm4.2/actin filaments alters neuronal signaling, neurite outgrowth and behavioral phenotypes in miceSemantic proximity Read ↗

Drosophila Homolog of the Human Carpenter Syndrome Linked Gene, MEGF8, Is Required for Synapse Development and Function.Semantic proximity Read ↗

Normal dynactin complex function during synapse growth in Drosophila requires membrane binding by Arfaptin.Semantic proximity Read ↗

Drosophila cyfip regulates synaptic development and endocytosis by suppressing filamentous actin assembly.Semantic proximity Read ↗

Tweek-dependent formation of ER-PM contact sites enables astrocyte phagocytic function and remodeling of neuronsSemantic proximity Read ↗

<i>Drosophila</i> Atlastin regulates synaptic vesicle mobilization independent of Bone Morphogenetic Protein signalingSemantic proximity Read ↗

The atypical cadherin flamingo regulates synaptogenesis and helps prevent axonal and synaptic degeneration in Drosophila.Semantic proximity Read ↗

The Crossroads of Synaptic Growth Signaling, Membrane Traffic and Neurological Disease: Insights from <i>Drosophila</i>Semantic proximity Read ↗

Drosophila Nesprin-1 controls glutamate receptor density at neuromuscular junctions.Semantic proximity Read ↗

Genetic and molecular analysis of synaptic vesicle recycling in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.