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Article

Moesin helps to restrain synaptic growth at the Drosophila neuromuscular junction.

Developmental neurobiology - 15 Feb 2008

Seabrooke Sara, Stewart Bryan A

Abstract excerpt

The precise role of actin and actin-binding proteins in synaptic development is unclear. In Drosophila, overexpression of a dominant-negative NSF2 construct perturbs filamentous actin, which is associated with overgrowth of the NMJ, while co-expression of moesin, which encodes an actin binding protein, suppresses this overgrowth phenotype. These data suggest that Moesin may play a role in synaptic development at...

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Identifiers

PMID: 18161855
DOI: 10.1002/dneu.20595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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