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Article

Highwire regulates synaptic growth in Drosophila.

Neuron - 1 May 2000

Wan H I, DiAntonio A, Fetter R D, Bergstrom K, Strauss R, Goodman C S

Abstract excerpt

The formation, stabilization, and growth of synaptic connections are dynamic and highly regulated processes. The glutamatergic neuromuscular junction (NMJ) in Drosophila grows new boutons and branches throughout larval development. A primary walking behavior screen followed by a secondary anatomical screen led to the identification of the highwire (hiw) gene. In hiw mutants, the specificity of motor axon...

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PMID: 10839352
DOI: 10.1016/s0896-6273(00)81166-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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