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Article

Drosophila MICAL regulates myofilament organization and synaptic structure.

Mechanisms of development - 1 May 2007

Beuchle Dirk, Schwarz Heinz, Langegger Maria, Koch Iris, Aberle Hermann

Abstract excerpt

The overall size and structure of a synaptic terminal is an important determinant of its function. In a large-scale mutagenesis screen, designed to identify Drosophila mutants with abnormally structured neuromuscular junctions (NMJs), we discovered mutations in Drosophila mical, a conserved gene encoding a multi-domain protein with a N-terminal monooxygenase domain. In mical mutants, synaptic boutons do not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17350233
DOI: 10.1016/j.mod.2007.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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