Article

Preclinical drug response metric based on cellular response phenotype provides better pharmacogenomic variables with phenotype relevance

2020-12-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Purpose</h4> Assessment of drug response is typically performed by constructing a dose-response curve of viability and summarizing it to a representative value. However, this is limited by its dependency on the assay duration and lack of reflections regarding actual cellular response phenotypes. To resolve these limitations, we considered contribution of each response phenoty...

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Literature Corpus work: 395963b8-73d1-5d9a-ba84-768ccf12f5a4
DOI: 10.1101/2020.12.23.424257

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