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Development of Drug-resistant Cell Lines for Experimental Procedures

12 Aug 2025

Abstract excerpt

The development of drug-resistant cell lines is essential for understanding the mechanisms of drug resistance and identifying strategies to overcome treatment failure in cancer therapy. Resistance models enable preclinical evaluation of novel compounds, repurposed drugs, and combination therapies. To generate resistant cells, parental cancer cell lines are repeatedly exposed to incrementally increasing...

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PMID: 40889269
DOI: 10.3791/68957

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