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Article

Simulation of cancer cell line pharmacogenomics data to optimise experimental design and analysis strategy

2017-08-11

Abstract excerpt

<h4>Background</h4> Explaining the variability in drug sensitivity across a panel of cell lines using genomic information is a key aspect of cancer drug discovery. The results of such analyses may ultimately determine which patients are likely to benefit from a new treatment. There are numerous experimental factors that can influence the outcomes of cell line screening panels such as the number of replicates, num...

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Literature Corpus work
dd30b7f0-b3be-50ec-9f80-9fa46de0d721
DOI
10.1101/174862
Open publication

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Simulation of cancer cell line pharmacogenomics data to optimise experimental design and analysis strategyDOI 10.1101/174862
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