Article

Drug GRADE: an integrated analysis of population growth and cell death reveals drug-specific and cancer subtype-specific response profiles

2020-02-27

Abstract excerpt

<h4>ABSTRACT</h4> In the pre-clinical evaluation of anti-cancer drugs, two different measurement approaches are used: relative viability, which scores an amalgam of growth arrest and cell death, and fractional viability, which more specifically scores the degree of cell killing. In this study, we directly quantify relationships between drug-induced growth inhibition and drug-induced cell death by counting live an...

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Literature Corpus work: ac824453-e0d0-5c65-a40e-fd2c4ebc53ef
DOI: 10.1101/2020.02.26.966689

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