Article

Structural Basis for Rapid Voltage Dependent Inactivation of HERG Potassium Channels

2021-12-08

Abstract excerpt

<title>Abstract</title> <p>The exquisite fine tuning of biological electrical signalling is mediated by variations in the rates of opening and closing of different ion channels(1). In addition to open and closed conformations, ion channels can exist in an inactivated state, which prevents conduction in the presence of a prolonged activating stimulus(2). Human ether-a-go-go related gene (HERG) K+ channels undergo...

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Literature Corpus work: 3777c288-e3a9-5e85-a01b-772ec5643830
DOI: 10.21203/rs.3.rs-1105661/v1

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