Article

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

2008-11-16

Abstract excerpt

Abstract Relapsed acute lymphoblastic leukemia (ALL) is the fourth most common pediatric malignancy and carries a dismal prognosis. To gain insights into the genetic alterations responsible for relapse, we performed genome-wide analysis of matched diagnosis and relapse samples from 61 pediatric ALL patients, including 47 B-progenitor and 14 T-ALL cases. All samples were flow sorted as required to ensure at least 8...

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Literature Corpus work: 376ac333-d8a6-5015-aac0-27d814041886
DOI: 10.1182/blood.v112.11.429.429

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