Article
Plasticity and biological diversity of myeloid derived suppressor cells.
Current opinion in immunology - 1 Apr 2018
Ben-Meir Kerem, Twaik Nira, Baniyash Michal
Abstract excerpt
Myeloid derived suppressor cells (MDSCs) are immature myeloid cells characterized by diverse phenotypes and functions. They impair effector functions of immune cells and promote tumor growth, angiogenesis, and tissue damage. In pathologies characterized by chronic inflammation, MDSCs are arrested in their immature state and migrate from the bone marrow to the periphery and to the site of inflammation, where they...
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