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Article

Redefining Tumor-Associated Macrophage Subpopulations and Functions in the Tumor Microenvironment.

Frontiers in immunology - 1 Jan 2020

Wu Kaiyue, Lin Kangjia, Li Xiaoyan, Yuan Xiangliang, Xu Peiqing, Ni Peihua, Xu Dakang

Abstract excerpt

The immunosuppressive status of the tumor microenvironment (TME) remains poorly defined due to a lack of understanding regarding the function of tumor-associated macrophages (TAMs), which are abundant in the TME. TAMs are crucial drivers of tumor progression, metastasis, and resistance to therapy. Intra- and inter-tumoral spatial heterogeneities are potential keys to understanding the relationships between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32849616
DOI: 10.3389/fimmu.2020.01731
PMCID: PMC7417513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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