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Single-cell map of diverse immune phenotypes in the acute myeloid leukemia microenvironment

1 Mar 2021

Abstract excerpt

Abstract Background Knowledge of immune cell phenotypes, function, and developmental trajectory in acute myeloid leukemia (AML) microenvironment is essential for understanding mechanisms of evading immune surveillance and immunotherapy response of targeting special microenvironment components. Methods Using a single-cell RNA sequencing (scRNA-seq) dataset, we analyzed the immune cell phenotypes, function, and...

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PMID: 33648605
DOI: 10.1186/s40364-021-00265-0

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