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Evolution and Targeting of Myeloid Suppressor Cells in Cancer: A Translational Perspective

20 Jan 2022

Abstract excerpt

In recent years, the immune system has emerged as a critical regulator of tumor development, progression and dissemination. Advanced therapeutic approaches targeting immune cells are currently under clinical use and improvement for the treatment of patients affected by advanced malignancies. Among these, anti-PD1/PD-L1 and anti-CTLA4 immune checkpoint inhibitors (ICIs) are the most effective immunotherapeutic...

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PMID: 35158779
DOI: 10.3390/cancers14030510

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