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Early memory deficits and extensive brain network disorganization in the App NL-F / MAPT double knock-in mouse model of familial Alzheimer’s disease

2021-04-13

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A critical challenge in current research on AD is to clarify the relationship between early neuropathology and network dysfunction associated to the emergence of subtle memory alterations which announce disease onset. In the present work, the new generation App NL-F / MAPT double knock in (dKI) model was used to evaluate early stages of AD. The initial step of tau pathology was restricted to the perirhinal-entor...

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Literature Corpus work: 358c497e-775a-52aa-a989-ccc08d50bf94
DOI: 10.1101/2021.04.11.439177

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Early memory deficits and extensive brain network disorganization in the App NL-F / MAPT double knock-in mouse model of familial Alzheimer’s diseaseDOI 10.1101/2021.04.11.439177Read

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Early memory deficits and extensive brain network disorganization in the <i>App</i> <sup> <i>NL-F</i> </sup> / <i>MAPT</i> double knock-in mouse model of familial Alzheimer’s disease

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