Article

Local structural dynamics of Rad51 protomers revealed by cryo-electron microscopy of Rad51-ssDNA filaments

2024-05-07

Abstract excerpt

<h4>ABSTRACT</h4> Homologous recombination (HR) is a high-fidelity repair mechanism for double-strand breaks. Rad51 is the key enzyme that forms filaments on single-stranded DNA (ssDNA) to catalyze homology search and DNA strand exchange in recombinational DNA repair. In this study, we employed single-particle cryo-electron microscopy (cryo-EM) to ascertain the density map of the budding yeast Rad51-ssDNA filamen...

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Literature Corpus work: 3564be2c-4ef4-502f-a23e-dfa30749e563
DOI: 10.1101/2024.05.06.592824

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