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Article

Crystal structure of a Rad51 filament.

Nature structural & molecular biology - 1 Aug 2004

Conway Adam B, Lynch Thomas W, Zhang Ying, Fortin Gary S, Fung Cindy W, Symington Lorraine S, Rice Phoebe A

Abstract excerpt

Rad51, the major eukaryotic homologous recombinase, is important for the repair of DNA damage and the maintenance of genomic diversity and stability. The active form of this DNA-dependent ATPase is a helical filament within which the search for homology and strand exchange occurs. Here we present the crystal structure of a Saccharomyces cerevisiae Rad51 filament formed by a gain-of-function mutant. This filament...

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PMID: 15235592
DOI: 10.1038/nsmb795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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