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Article

Rad51 paralog complex Rad55–Rad57 acts as a molecular chaperone during homologous recombination

2020-11-04

Abstract excerpt

<h4>Summary</h4> Homologous recombination (HR) is essential for the maintenance of genome integrity. Rad51 paralogs fulfill a conserved, but undefined role in HR, and their mutations are associated with increased cancer risk in humans. Here, we use single–molecule imaging to reveal that the Saccharomyces cerevisiae Rad51 paralog complex Rad55–Rad57 promotes the assembly of Rad51 recombinase filaments through tra...

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Identifiers and source

Literature Corpus work
c5620f76-ee44-5776-aca7-c73db2d01c9c
DOI
10.1101/2020.11.04.367136
Open publication

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Rad51 paralog complex Rad55–Rad57 acts as a molecular chaperone during homologous recombinationDOI 10.1101/2020.11.04.367136
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